second-line
B2CEFR level
45/100Rarity: uncommon
TechnicalRegister
Describing a treatment used when the first choice has failed or cannot be tolerated.
We moved to a second-line antibiotic after the initial course did not clear the infection.
Rarity runs from 0 (a word everyone knows) to 100 (almost never seen outside specialist or literary writing). Level is the word's real difficulty on the CEFR scale, from A1 to C2.
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